Acute viral myocarditis: role of immunosuppression: a prospective randomised study

@article{Aziz2010AcuteVM,
  title={Acute viral myocarditis: role of immunosuppression: a prospective randomised study},
  author={Kalim Uddin Aziz and Najma Patel and Tareen Sadullah and Habiba Tasneem and Hasina Thawerani and Saeed Talpur},
  journal={Cardiology in the Young},
  year={2010},
  volume={20},
  pages={509 - 515}
}
Abstract Objective To conduct a prospective randomised study to show the efficacy of immune suppression with prednisolone, administered at the 3-month duration of acute myocarditis. Methods The diagnosis of acute viral myocarditis was made based on echocardiography and serum viral antibodies. The inclusion criterion was acute myocarditis of 3 months duration. In all, 68 of 173 children were available for randomisation into a prednisolone-treated group of 44 and a control group of 24 children… 

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Immunosuppressive treatment for myocarditis: a meta-analysis of randomized controlled trials

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It was revealed that high-dose steroid or IVIG therapy had no significant effects on major in-hospital complications, late heart failure hospitalization, and long-term mortality.

Corticosteroids for viral myocarditis.

For people diagnosed with viral myocarditis and low LVEF, corticosteroids do not reduce mortality but they may improve cardiac function but the trials were of low quality and small size so this finding must be regarded as uncertain.

Management of acute myocarditis in children.

Myocarditis is a challenging diagnosis to make on clinical grounds and requires high index of suspicion, but the overall prognosis of the disease is good with survival rates up to 80%.

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