Acute troglitazone action in isolated perfused rat liver.

@article{Preininger1999AcuteTA,
  title={Acute troglitazone action in isolated perfused rat liver.},
  author={K Preininger and Harald Stingl and R. Englisch and Clemens F{\"u}rnsinn and Juergen Graf and Werner Waldh{\"a}usl and Michael Roden},
  journal={British journal of pharmacology},
  year={1999},
  volume={126 1},
  pages={
          372-8
        }
}
1. The thiazolidinedione compound, troglitazone, enhances insulin action and reduces plasma glucose concentrations when administered chronically to type 2 diabetic patients. 2. To analyse to what extent thiazolidinediones interfere with liver function, we examined the acute actions of troglitazone (0.61 and 3.15 microM) on hepatic glucose and lactate fluxes, bile secretion, and portal pressure under basal, insulin- and/or glucagon-stimulated conditions in isolated perfused rat livers. 3. During… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 26 CITATIONS

Effects of troglitazone on HepG2 viability and mitochondrial function.

VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED