Acute treatment with morphine augments the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain.

@article{Yoshikawa2005AcuteTW,
  title={Acute treatment with morphine augments the expression of serine racemase and D-amino acid oxidase mRNAs in rat brain.},
  author={M. Yoshikawa and H. Andoh and Kenji Ito and Toshiyasu Suzuki and M. Kawaguchi and Hiroyuki Kobayashi and T. Oka and A. Hashimoto},
  journal={European journal of pharmacology},
  year={2005},
  volume={525 1-3},
  pages={
          94-7
        }
}
To obtain further insight into the interactions between the N-methyl-D-aspartate receptor and opioid receptor systems, we have investigated the effects of the acute treatment of morphine on the expression of serine racemase and D-amino acid oxidase mRNAs in several brain areas of rats. The morphine administration produced a dose-dependent and transient elevation in the levels of serine racemase and D-amino acid oxidase mRNAs in all the brain areas. The present results are the first to suggest… Expand
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