Acute toxicity of taxine in mice and rats.

  • Yalcin Tekol
  • Published 1991 in Veterinary and human toxicology


The acute toxicity of taxine isolated from leaves of yew trees was determined in mice and rats. The drug was used as the sulphate salt. The following LD50 values (mg/kg) and 95% confidence limits were found: mice po 19.72 (16.84-23.09); mice ip 21.88 (19.66-24.35); rats sc 20.18 (18.35-22.20). 


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