Acute toxicity of nickel nanoparticles in rats after intravenous injection

@inproceedings{Magaye2014AcuteTO,
  title={Acute toxicity of nickel nanoparticles in rats after intravenous injection},
  author={Ruth R Magaye and Xia Li Yue and Baobo Zou and Hongbo Shi and Hongsheng Yu and Kui Kui Liu and Xialu Lin and Jin dan Xu and Cui Wei Yang and Aiguo Wu and Jinshun Zhao},
  booktitle={International journal of nanomedicine},
  year={2014}
}
This study was carried out to add scientific data in regard to the use of metallic nanoparticles in nanomedicine. The acute toxicity of nickel (Ni) nanoparticles (50 nm), intravenously injected through the dorsal penile vein of Sprague Dawley rats was evaluated in this study. Fourteen days after injection, Ni nanoparticles induced liver and spleen injury, lung inflammation, and caused cardiac toxicity. These results indicate that precautionary measures should be taken with regard to the use of… CONTINUE READING