Acute toxicity and the 28-day repeated dose study of a Siddha medicine Nuna Kadugu in rats

@inproceedings{Ramaswamy2012AcuteTA,
  title={Acute toxicity and the 28-day repeated dose study of a Siddha medicine Nuna Kadugu in rats},
  author={Ramaswamy Selvaratnam Ramaswamy and Nettam Prathyusha and Ruthiramoorthi Saranya and Haridass Sumathy and Kutuva Tulasi Mohanavalli and Raju Jyothi Priya and Jayakothanda Ramaswamy Venkhatesh and Chidambaram Saravana Babu and Kumarasamy Manickavasakam and Sadagopan Thanikachalam},
  booktitle={BMC complementary and alternative medicine},
  year={2012}
}
BACKGROUND Nuna Kadugu (NK), a Siddha medicine prepared from leaves and fruits of Morinda Pubescens, used for the treatment of various skin diseases. Though NK has been widely used for several decades, no scientific report was available on its safety. Present study was undertaken to demonstrate the oral toxicity of NK in Sprague Dawley rats. METHODS Acute and 28-day repeated oral toxicity studies were performed following OECD test guidelines 423 and 407, respectively, with minor modifications… CONTINUE READING
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