Acute toxicity and general pharmacological effect on central nervous system of the crude rhizome extract of Kyllinga brevifolia Rottb.

Abstract

Acute toxicity and general pharmacological activities of the crude hydro-alcoholic rhizome extract of Kyllinga brevifolia Rottb., a popular medicine used in Paraguay, were investigated on mice. The intraperitoneal LD50 was found to be 575 mg/kg. Oral administration of doses up to 3.0 g/kg did not provoke any toxic symptoms. Oral administration of 100 mg/kg… (More)

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@article{HellinIbarrola1999AcuteTA, title={Acute toxicity and general pharmacological effect on central nervous system of the crude rhizome extract of Kyllinga brevifolia Rottb.}, author={M C Helli{\"o}n-Ibarrola and Derlis A. Ibarrola and Y. Montalbetti and Dar{\'i}o Salvador Villalba and O Y Heinichen and E. Ferro}, journal={Journal of ethnopharmacology}, year={1999}, volume={66 3}, pages={271-6} }