Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.

@article{Ike2002AcuteTM,
  title={Acute toxicity, mutagenicity, and estrogenicity of biodegradation products of bisphenol-A.},
  author={Michihiko Ike and Min-Yu Chen and C Jin and Masanori Fujita},
  journal={Environmental toxicology},
  year={2002},
  volume={17 5},
  pages={457-61}
}
Biodegradation of bisphenol-A (BPA), which is known as an estrogenic chemical, proceeds via complicated metabolic routes and leads to formation of several kinds of biodegradation products. Through the major route BPA can be completely mineralized; however, p-hydroxyacetophenone (p-HAP), p-hydroxybenzaldehyde (p-HBAL), and p-hydroxybenzoic acid (p-HBA) are transiently accumulated at relatively high concentrations. On the other hand, degradation of BPA through the minor route tends to cause the… CONTINUE READING