Acute toxic effects of an isolate of moniliformin-producing Fusarium oxysporum and purified moniliformin on rats.

@article{Abbas1990AcuteTE,
  title={Acute toxic effects of an isolate of moniliformin-producing Fusarium oxysporum and purified moniliformin on rats.},
  author={Hamed K Abbas and Chester J. Mirocha and Ronald F. Vesonder and Roland L. Gunther},
  journal={Archives of environmental contamination and toxicology},
  year={1990},
  volume={19 3},
  pages={433-6}
}
An isolate of Fusarium oxysporum (MT-6) was obtained from pasture soil in New Zealand in 1987. The isolate was grown on rice and fed to rats in a ratio of 50% and 10% of a complete diet. All rats died within 16 hr and showed mild intestinal and thymic hemorrhage. The major identifiable toxin was moniliformin found at a concentration of 9 mg/g in the rice culture. Purified crystals of moniliformin fed to rats at concentrations of 8, 5 and 3 mg/g of rat diet caused hemorrhaging in the intestines… CONTINUE READING