Acute topiramate overdose – clinical manifestations

@article{Winiewski2009AcuteTO,
  title={Acute topiramate overdose – clinical manifestations},
  author={Marek Wiśniewski and Magdalena Łukasik-Głębocka and Jacek Sein Anand},
  journal={Clinical Toxicology},
  year={2009},
  volume={47},
  pages={317 - 320}
}
Introduction. The clinical manifestations of acute topiramate toxicity are described. Methods. Seven cases of acute and acute-on-chronic topiramate toxicity observed in two clinical units of Polish Poison Control Centers in 2004–2005 were analyzed. Results. The patients were 4 women and 2 men aged between 16 and 38 (mean 21.0 ± 8.4) years. The doses of topiramate ranged from 10.7 to 218 mg/kg. The most frequent symptom was somnolence (66.7%) and, vertigo, agitation, and mydriasis were less… Expand
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