Acute systolic dysfunction within two weeks of high-dose chemotherapy conditioning before autologous bone marrow transplant: a case report.

@article{Gupta2008AcuteSD,
  title={Acute systolic dysfunction within two weeks of high-dose chemotherapy conditioning before autologous bone marrow transplant: a case report.},
  author={R Gupta and Christina M Murray and Ralph Lazzara and Chittur A. Sivaram},
  journal={Echocardiography},
  year={2008},
  volume={25 7},
  pages={764-7}
}
Studies have shown various cardiotoxic effects of high-dose chemotherapy (HDC) used for conditioning before autologous bone marrow transplant (ABMT) including arrhythmias but only a transient small decrease in left ventricle ejection fraction (LVEF). To our knowledge, an acute dramatic decrease in LVEF after HDC preconditioning has never been reported. We… CONTINUE READING