Acute stress-induced hyperinsulinemia in the pertussis toxin-treated rat: possible role of humoral beta-cell-tropic factors.

Abstract

The present study was undertaken to determine if acute stress induced by exposure to ether resulted in the presence of beta-cell-tropic factors in rat plasma and if this insulinotropic activity was increased by pertussis toxin. Rats pretreated with pertussis toxin (5 micrograms/kg, 5 days previously) showed marked hyperinsulinemia, but only after exposure… (More)

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