Acute stress enhances while chronic stress suppresses skin immunity. The role of stress hormones and leukocyte trafficking.

@article{Dhabhar2000AcuteSE,
  title={Acute stress enhances while chronic stress suppresses skin immunity. The role of stress hormones and leukocyte trafficking.},
  author={Firdaus S. Dhabhar},
  journal={Annals of the New York Academy of Sciences},
  year={2000},
  volume={917},
  pages={876-93}
}
Delayed-type hypersensitivity (DTH) reactions are antigen-specific, cell-mediated immune responses that, depending on the antigen, mediate beneficial (resistance to viruses, bacteria, fungi) or harmful (allergic dermatitis, autoimmunity) aspects of immunity. Contrary to the widely held notion that stress is immunosuppressive, we have shown that under certain conditions, stress can enhance immune function. DTH reactions can be studied in rats or mice by challenging the pinnae of previously… CONTINUE READING

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