Acute stress disrupts paired pulse facilitation and long-term potentiation in rat dorsal hippocampus through activation of glucocorticoid receptors.

@article{Cazakoff2010AcuteSD,
  title={Acute stress disrupts paired pulse facilitation and long-term potentiation in rat dorsal hippocampus through activation of glucocorticoid receptors.},
  author={Brittany N. Cazakoff and John G Howland},
  journal={Hippocampus},
  year={2010},
  volume={20 12},
  pages={
          1327-31
        }
}
Cognitive functions such as learning and memory are widely believed to depend on patterns of short- and long-term synaptic plasticity. Factors, such as acute stress, which affect learning and memory, may do so by altering patterns of synaptic plasticity in distinct neural circuits. Numerous studies have examined the effects of acute stress on long-term synaptic plasticity; however, few have examined its influence on short-term plasticity. The present experiments directly assessed the effects of… CONTINUE READING

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