Acute stimulation in the external segment of the globus pallidus improves parkinsonian motor signs.

@article{Vitek2004AcuteSI,
  title={Acute stimulation in the external segment of the globus pallidus improves parkinsonian motor signs.},
  author={Jerrold L. Vitek and Takao Hashimoto and John Peoples and Mahlon R. Delong and R. Bakay},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2004},
  volume={19 8},
  pages={907-15}
}
High frequency (>100Hz) electrical stimulation in both the external (GPe) and internal (GPi) segments of the globus pallidus was effective in improving parkinsonian motor signs. Improvement generally occurred at short latency (<5-10 seconds) in both GPe and GPi but was often (50% of the time) delayed in GPi. Dyskinetic movements were observed during stimulation within GPe and GPi but were more frequent in GPe (20% vs. 9%). These findings suggest that electrical stimulation in both GPe and GPi… CONTINUE READING