Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration.


Sleep deprivation induces acute inflammation and increased glucocorticosteroids in vertebrates, but effects from fragmented, or intermittent, sleep are poorly understood. Considering the latter is more representative of sleep apnea in humans, we investigated changes in proinflammatory (IL-1β, TNF-α) and anti-inflammatory (TGF-β1) cytokine gene expression in… (More)
DOI: 10.1152/ajpregu.00049.2015

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