Acute sleep deprivation enhances avoidance learning and spatial memory and induces delayed alterations in neurochemical expression of GR, TH, DRD1, pCREB and Ki67 in rats.

@article{Azogu2015AcuteSD,
  title={Acute sleep deprivation enhances avoidance learning and spatial memory and induces delayed alterations in neurochemical expression of GR, TH, DRD1, pCREB and Ki67 in rats.},
  author={Idu Azogu and Patricia Barra de la Tremblaye and Megan Dunbar and Marianne Lebreton and Nathalie Lemarec and H{\'e}l{\`e}ne Plamondon},
  journal={Behavioural brain research},
  year={2015},
  volume={279},
  pages={177-90}
}
The current study investigated the effects of acute versus repeated periods of sleep deprivation on avoidance learning and spatial memory and on the expression of discrete biochemical brain signals involved in stress regulation, motivation and brain plasticity. Male Long-Evans rats were sleep deprived using the platform-over-water method for a single 4 h… CONTINUE READING