Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test

@inproceedings{Crestani2009AcuteRI,
  title={Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test},
  author={Carlos C Crestani and Fernando H. F. Alves and Fernando MA Correa and Francisco S Guimar{\~a}es and S{\^a}mia Regiane Lourenço Joca},
  booktitle={Behavioral and Brain Functions},
  year={2009}
}
The bed nucleus of stria terminalis (BNST) is a limbic forebrain structure involved in hypothalamo-pituitary-adrenal axis regulation and stress adaptation. Inappropriate adaptation to stress is thought to compromise the organism's coping mechanisms, which have been implicated in the neurobiology of depression. However, the studies aimed at investigating BNST involvement in depression pathophysiology have yielded contradictory results. Therefore, the objective of the present study was to… CONTINUE READING
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