Acute respiratory tract infections and mannose-binding lectin insufficiency during early childhood.

@article{Koch2001AcuteRT,
  title={Acute respiratory tract infections and mannose-binding lectin insufficiency during early childhood.},
  author={Anders Koch and Mads Melbye and Per Hvidkj{\ae}r S\orensen and Preben Hom\oe and Hans Ole Madsen and K{\aa}re M\olbak and Christoffer Holst Hansen and Lasse H\ogh Andersen and Gitte Weinkauff Hahn and Peter Garred},
  journal={JAMA},
  year={2001},
  volume={285 10},
  pages={1316-21}
}
CONTEXT Hospital-based studies have found that increased susceptibility to certain infections is associated with low serum levels of mannose-binding lectin (MBL) due to MBL variant alleles. However, the contribution of MBL insufficiency to incidence of common childhood infections at a population level is unknown. OBJECTIVE To investigate the effect of MBL insufficiency on risk for acute respiratory tract infection (ARI) in unselected children younger than 2 years. DESIGN AND SETTING… CONTINUE READING