Acute renal failure in the "Comrades Marathon" runners.

@article{Seedat1989AcuteRF,
  title={Acute renal failure in the "Comrades Marathon" runners.},
  author={Yackoob Kassim Seedat and N Aboo and Selvaraj Naicker and I Parsoo},
  journal={Renal failure},
  year={1989},
  volume={11 4},
  pages={209-12}
}
This study investigated the clinical and biochemical features of acute renal failure in marathon runners. Over a period of 18 years (1969-1986), 19 patients were admitted to the renal unit. The histories and biochemical data of 4 patients seen in 1986 are described. The pathophysiology of acute renal failure is multifactorial and is the combined effect of rhabdomyolysis, dehydration, hypotension, nonsteroidal anti-inflammatory drugs, and hyperuricaemia. Efforts to correct dehydration have… CONTINUE READING

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