Acute renal failure in Rocky Mountain spotted fever.

  title={Acute renal failure in Rocky Mountain spotted fever.},
  author={David H Walker and William D Mattern},
  journal={Archives of internal medicine},
  volume={139 4},
Review of clinical and pathologic data from ten fatal cases of Rocky Mountain spotted fever (RMSF) revealed the importance of acute renal failure in the clinical course and of multifocal perivascular interstitial nephritis as the principal pathologic lesion. In nine cases, Rickettsia rickettsii were demonstrated by immunofluorescence in the areas of vasculitis. Evidence was lacking for the role of disseminated intravascular coagulation, glomerulonephritis, or myoglobinuria in the pathogenesis… CONTINUE READING
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