Acute renal failure due to acetaminophen ingestion: a case report and review of the literature.

@article{Blakely1995AcuteRF,
  title={Acute renal failure due to acetaminophen ingestion: a case report and review of the literature.},
  author={Patricia Blakely and B. R. McDonald},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1995},
  volume={6 1},
  pages={48-53}
}
Acetaminophen is the most commonly reported drug overdose in the United States. Acute renal failure occurs in less than 2% of all acetaminophen poisonings and 10% of severely poisoned patients. At the therapeutic dosages, acetaminophen can be toxic to the kidneys in patients who are glutathione depleted (chronic alcohol ingestion, starvation, or fasting) or who take drugs that stimulate the P-450 microsomal oxidase enzymes (anticonvulsants). Acute renal failure due to acetaminophen manifests as… CONTINUE READING
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