Acute renal failure by ingestion of Cortinarius species confounded with psychoactive mushrooms: a case series and literature survey.

@article{Frank2009AcuteRF,
  title={Acute renal failure by ingestion of Cortinarius species confounded with psychoactive mushrooms: a case series and literature survey.},
  author={Helga Frank and Th Zilker and Martin Kirchmair and Florian Eyer and Bettina Haberl and G Tuerkoglu-Raach and Matthias Wessely and H J Gr{\"o}ne and Uwe W Heemann},
  journal={Clinical nephrology},
  year={2009},
  volume={71 5},
  pages={557-62}
}
Mushrooms of the Cortinarius species are nephrotoxic and can cause severe acute renal failure. The toxic effect is due to orellanine. It is suspected that the cytotoxic damage is caused by the production of oxygen-free radicals. Renal pathology shows tubular necrosis with interstitial nephritis. In addition to accidental intoxications as a consequence of mushroom meals, recent cases are often due to voluntary abuse of natural drugs like magic mushrooms. We report 4 current cases of acute renal… CONTINUE READING
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