Acute renal failure and its risk factors in Stevens-Johnson syndrome and toxic epidermal necrolysis.

@article{Hung2009AcuteRF,
  title={Acute renal failure and its risk factors in Stevens-Johnson syndrome and toxic epidermal necrolysis.},
  author={Chi-Chih Hung and Wan-Chun Liu and M C Kuo and Chih-Hung Lee and Shang-Jyh Hwang and Hung-Chun Chen},
  journal={American journal of nephrology},
  year={2009},
  volume={29 6},
  pages={633-8}
}
BACKGROUND Skin lesion is the most frequent manifestation of adverse drug reactions. Drug-induced cutaneous hypersensitivity and drug-induced acute interstitial nephritis might share a similar mechanism involving drug-specific T cells. We thus investigated the renal outcome of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), the most severe drug-induced cutaneous hypersensitivity, and hypothesize that skin detachment in SJS/TEN might be associated with acute renal failure… CONTINUE READING

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