Acute renal failure and hyperkalaemia associated with cyclooxygenase-2 inhibitors.

@article{Braden2004AcuteRF,
  title={Acute renal failure and hyperkalaemia associated with cyclooxygenase-2 inhibitors.},
  author={Gregory Braden and Michael H. O'Shea and Jeffrey G. Mulhern and Michael J. Germain},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2004},
  volume={19 5},
  pages={1149-53}
}
BACKGROUND The renal effects of cyclooxygenase-2 (COX-2) inhibitors have been incompletely elucidated, and acute renal failure (ARF) due to COX-2 inhibitors has been reported. METHODS In order to determine the causes of ARF and hyperkalaemia in five patients during COX-2 inhibitor therapy, we carefully analysed case studies of consecutive in-patients or out-patients referred to our Renal Division over a 6-month period for ARF and hyperkalaemia who had recently received COX-2 inhibitors… CONTINUE READING