Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats.

@article{Hamazaki1985AcuteRF,
  title={Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats.},
  author={Shuji Hamazaki and Shigeru Okada and Yoshihito Ebina and Osamu Midorikawa},
  journal={Toxicology and applied pharmacology},
  year={1985},
  volume={77 2},
  pages={267-74}
}
Nitrilotriacetate (NTA), an effective metal-chelating agent, has been used as a substitute for polyphosphates in household laundry detergents. Nephrotoxicity and renal tumorigenicity have been reported in experimental animals that received high doses of NTA po for 4 weeks to 2 years. Since NTA exists in water as a variety of NTA-metal complexes, it was important to investigate the biological effects of NTA in a complexed form. In this study, acute and subchronic toxicity of a ferric iron… CONTINUE READING
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