Acute renal failure: clinical aspects and pathophysiology.

  title={Acute renal failure: clinical aspects and pathophysiology.},
  author={Jay H. Stein and R V Patak and Meyer D. Lifschitz},
  journal={Contributions to nephrology},
Acute renal failure may be caused by multiple conditions including those which are due to some direct hemodynamic or nephrotoxic insult. In considering the pathophysiology of these entities, it seems appropriate to differentiate between the initiating and the maintenance phase of the disorder. In the former, renal ischemia and/or a direct effect of a given nephrotoxic agent seems to be the basis for the underlying renal damage. In the maintenance phase, renal functional impairment is maintained… CONTINUE READING


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