Acute rejection after renal transplantation is reduced by approximately 50% by prior therapeutic blood transfusions, even in tacrolimus-treated patients.

@article{Higgins2004AcuteRA,
  title={Acute rejection after renal transplantation is reduced by approximately 50% by prior therapeutic blood transfusions, even in tacrolimus-treated patients.},
  author={Robert Higgins and Neil T. Raymond and Nithya S. Krishnan and Murugu Veerasamy and Mohammad Rahmati and For Tai Lam and Habib Kashi and Nick West},
  journal={Transplantation},
  year={2004},
  volume={77 3},
  pages={469-71}
}
BACKGROUND The authors investigated the relationship between therapeutic blood transfusion before renal transplantation and rejection rates in cyclosporine- and tacrolimus-treated patients. METHODS In one center, 265 consecutive recipients were studied. Protocol induction was with azathioprine, prednisolone, and cyclosporine or tacrolimus; 37% had biopsy-proven acute rejection in the first 6 months and 46% had received zero to two units of blood before transplantation. RESULTS Lower risk of… CONTINUE READING