Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients.

@article{Gunnell1999AcutephaseRP,
  title={Acute-phase response predicts erythropoietin resistance in hemodialysis and peritoneal dialysis patients.},
  author={J. Gunnell and J. Yeun and T. Depner and G. Kaysen},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1999},
  volume={33 1},
  pages={
          63-72
        }
}
  • J. Gunnell, J. Yeun, +1 author G. Kaysen
  • Published 1999
  • Medicine
  • American journal of kidney diseases : the official journal of the National Kidney Foundation
We defined erythropoietin (EPO) resistance by the ratio of the weekly EPO dose to hematocrit (Hct), yielding a continuously distributed variable (EPO/Hct). EPO resistance is usually attributed to iron or vitamin deficiency, hyperparathyroidism, aluminum toxicity, or inflammation. Activation of the acute-phase response, assessed by the level of the acute-phase C-reactive protein (CRP), correlates strongly with hypoalbuminemia and mortality in both hemodialysis (HD) and peritoneal dialysis (PD… Expand
Serum albumin is strongly associated with erythropoietin sensitivity in hemodialysis patients.
Nutritional-inflammation status and resistance to erythropoietin therapy in haemodialysis patients.
  • F. Locatelli, S. Andrulli, +9 authors C. Zoccali
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2006
Factors related to erythropoietin hypo-responsiveness in patients on chronic peritoneal dialysis
Effect of malnutrition-inflammation complex syndrome on EPO hyporesponsiveness in maintenance hemodialysis patients.
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  • American journal of kidney diseases : the official journal of the National Kidney Foundation
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