Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis.

  title={Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis.},
  author={Joseph Gerard Cannon and Simin Nikbin Meydani and Roger A Fielding and Maria A. Fiatarone and Mohsen Meydani and Mojtaba Farhangmehr and S. F. Orencole and Jeffrey B. Blumberg and William J Evans},
  journal={The American journal of physiology},
  volume={260 6 Pt 2},
Cytokines such as interleukin 1 (IL-1), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) mediate a variety of host responses to trauma and infection, including skeletal muscle proteolysis. This investigation assesses the influence of damaging eccentric exercise on in vitro production and plasma concentrations of cytokines and their relationship to muscle protein breakdown. In a double-blind placebo-controlled protocol, 21 male subjects took vitamin E supplements (800 IU/day… 

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