Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice.

@article{Renckens2008AcutePR,
  title={Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice.},
  author={Rosemarijn Renckens and David J. van Westerloo and Joris J. T. H. Roelofs and Jennie M. Pater and Marcus J. Schultz and Sandrine Florquin and Tom van der Poll},
  journal={Critical care medicine},
  year={2008},
  volume={36 2},
  pages={580-7}
}
OBJECTIVE Pseudomonas aeruginosa is a common pathogen in hospital-acquired pneumonia. Especially trauma and postsurgical patients display a profound acute phase protein response and are susceptible to acquiring pneumonia. The objective was to study the influence of the acute phase response induced by sterile tissue injury on pulmonary host defense. DESIGN… CONTINUE READING