Acute perilymphatic perfusion of the guinea pig cochlea.

A method for the continuous perfusion of the perilymphatic space of the inner ear in the guinea pig is described. Artificial perilymph is supplied to the cochlea and drained away through a tubing system while flow rates from 10 microliters/min to 0.3 ml/min are established by gravity syphon pressure. Techniques are also presented which allow control over… (More)