Acute panretinal structural and functional abnormalities after intravitreous ocriplasmin injection.

@article{Fahim2014AcutePS,
  title={Acute panretinal structural and functional abnormalities after intravitreous ocriplasmin injection.},
  author={Abigail T. Fahim and Naheed W Khan and Mark W. Johnson},
  journal={JAMA ophthalmology},
  year={2014},
  volume={132 4},
  pages={484-6}
}
IMPORTANCE Ocriplasmin cleaves fibronectin and laminin, components of the vitreous gel, and is used as a pharmacologic treatment for vitreomacular traction. Laminin is also found throughout multiple retinal layers. Ocriplasmin injection may lead to acute panretinal dysfunction in some eyes, but the mechanism of this toxic reaction has not been described. OBSERVATIONS We evaluated a 63-year-old woman demonstrating acute panretinal dysfunction after intravitreous ocriplasmin injection for a small… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 6 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 37 extracted citations

Biomechanical Properties of the Internal Limiting Membrane after Intravitreal Ocriplasmin Treatment.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde • 2016

References

Publications referenced by this paper.
Showing 1-8 of 8 references

and Drug Administration

US Foo
FDA approves Jetrea for symptomatic vitreomacular adhesion in the eyes [press release]. Updated October 18, 2012. http://www.fda.gov/NewsEvents/Newsroom /PressAnnouncements/ucm324369.htm. Accessed August 3, • 2013

FDA approves Jetrea for symptomatic vitreomacular adhesion in the eyes [ press release ]

M Hermel, MK Hartzer
2012

Laminin expression in adult and developing retinae: evidence of two novel CNS laminins.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000

Similar Papers

Loading similar papers…