Acute pancreatitis in children with acute lymphoblastic leukemia treated with L-asparaginase.

@article{FloresCaldern2009AcutePI,
  title={Acute pancreatitis in children with acute lymphoblastic leukemia treated with L-asparaginase.},
  author={Judith Flores-Calder{\'o}n and Emma Beatriz Exiga-Gonz{\'a}lez and Segundo Mor{\'a}n-Villota and Jorge Mart{\'i}n-Trejo and Alfonso Yamamoto-Nagano},
  journal={Journal of pediatric hematology/oncology},
  year={2009},
  volume={31 10},
  pages={790-3}
}
BACKGROUND L-asparaginase (L-asp) is used as part of the initial treatment in children with acute lymphoblastic leukemia (ALL), inducing remission in 83% to 95% of the treated patients. Major toxicity effects reported are hypersensitivity reactions and dysfunctions of the liver and pancreas. Acute pancreatitis (AP) induced by L-asp has been noted in 2.5% to 16% of the treated patients. The purpose of this study was to determine the frequency and outcome of AP in children with ALL treated with L… CONTINUE READING

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