Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: association with genetic polymorphism in DNA DSB repair genes.

@article{Ren2014AcuteOM,
  title={Acute oral mucositis in nasopharyngeal carcinoma patients treated with radiotherapy: association with genetic polymorphism in DNA DSB repair genes.},
  author={Jing-hua Ren and Xiao-fang Dai and Guo-Li Yan and Min Jin and Cui-wei Liu and Kun-Yu Yang and Gang Wu and C-M Charlie Ma},
  journal={International journal of radiation biology},
  year={2014},
  volume={90 3},
  pages={
          256-61
        }
}
PURPOSE The aim of this study was to investigate the association between polymorphic variants of DNA repair genes with the susceptibility of acute oral mucositis (OM) in nasopharyngeal carcinoma (NPC) patients treated with radiotherapy. MATERIALS AND METHODS The study population consisted of 120 NPC patients treated with intensity-modulated radiation therapy (IMRT). Among them 70 patients also received concurrent chemotherapy. Genotypes in DNA repair genes Ku70 c.-1310C>G (rs2267437), Ku70 c… CONTINUE READING
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