Acute or Chronic Life-Threatening Diseases Associated With Epstein-Barr Virus Infection

@article{Okano2012AcuteOC,
  title={Acute or Chronic Life-Threatening Diseases Associated With Epstein-Barr Virus Infection},
  author={Motohiko Okano and Thomas G. Gross},
  journal={The American Journal of the Medical Sciences},
  year={2012},
  volume={343},
  pages={483–489}
}
  • M. Okano, T. Gross
  • Published 1 June 2012
  • Medicine, Biology
  • The American Journal of the Medical Sciences
Abstract: Infectious mononucleosis (IM) is one of the representative, usually benign, acute diseases associated with primary Epstein-Barr virus (EBV) infection. IM is generally self-limiting and is characterized mostly by transient fever, lymphadenopathy and hepatosplenomegaly. However, very rarely primary EBV infection results in severe or fatal conditions such as hemophagocytic lymphohistiocytosis together with fulminant hepatitis designated as severe or fatal IM or EBV-associated… 
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