Acute-on-chronic liver failure in cirrhosis

  title={Acute-on-chronic liver failure in cirrhosis},
  author={Vicente Arroyo and Richard Moreau and Patrick Sequeira Kamath and Rajiv Jalan and Pere Gin{\`e}s and Frederik Nevens and J. Fern{\'a}ndez and Uyen To and G Garcia-Tsao and Bernd E. Schnabl},
  journal={Nature Reviews Disease Primers},
The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium guidelines, which defines this condition as a syndrome that develops in patients with cirrhosis and is characterized by acute decompensation, organ failure and high short-term mortality. One-third of patients who are hospitalized for acute decompensation… CONTINUE READING
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