Acute nicotine injections induce c-fos mostly in non-dopaminergic neurons of the midbrain of the rat.

@article{Pang1993AcuteNI,
  title={Acute nicotine injections induce c-fos mostly in non-dopaminergic neurons of the midbrain of the rat.},
  author={Y Pang and Hiroshi Kiba and Anusha Jayaraman},
  journal={Brain research. Molecular brain research},
  year={1993},
  volume={20 1-2},
  pages={162-70}
}
Induction of c-fos gene is an immediate and early response in the cascade of molecular events that ultimately lead to long-term alterations in gene expression in neurons. The psychomotor stimulant and positive reinforcing effects of nicotine have been speculated to be mediated by the dopaminergic neurons of the ventral tegmental area (VTA). To identify the precise subsets of VTA neurons of the rat that mediate the acute nicotinergic effects, the pattern of expression of c-fos gene was mapped… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Drugs of abuse and immediate-early genes in the forebrain

Molecular Neurobiology • 1998
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…