Acute nicotine enhances spontaneous recovery of contextual fear and changes c-fos early gene expression in infralimbic cortex, hippocampus, and amygdala.

@article{Kutlu2016AcuteNE,
  title={Acute nicotine enhances spontaneous recovery of contextual fear and changes c-fos early gene expression in infralimbic cortex, hippocampus, and amygdala.},
  author={Munir Gunes Kutlu and Jessica M. Tumolo and Erica D Holliday and Brendan Garrett and Thomas J Gould},
  journal={Learning & memory},
  year={2016},
  volume={23 8},
  pages={405-14}
}
Exposure therapy, which focuses on extinguishing fear-triggering cues and contexts, is widely used to treat post-traumatic stress disorder (PTSD). Yet, PTSD patients who received successful exposure therapy are vulnerable to relapse of fear response after a period of time, a phenomenon known as spontaneous recovery (SR). Increasing evidence suggests ventral hippocampus, basolateral amygdala, and infralimbic cortex may be involved in SR. PTSD patients also show high rates of comorbidity with… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
4 Citations
57 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 57 references

differentially modulate contextual fear conditioning

  • MG Kutlu, TJ Gould
  • 2014
Highly Influential
4 Excerpts

High - affinity a 4 b 2 nicotinic receptors mediate the impairing effects of acute nicotine on contextual fear extinction

  • V Laurent, RF Westbrook
  • Neurobiol Learn Mem
  • 2009
Highly Influential
4 Excerpts

Projections of the medial and lateral prefrontal cortices to the amygdala : a Phaseolus vulgaris leucoagglutinin study in the rat

  • MR Milad, GJ Quirk
  • Neuroscience
  • 2002
Highly Influential
4 Excerpts

The effects of acute nicotine on contextual safety discrimination

  • MG Kutlu, E Holliday, TJ Gould
  • J Psychopharmacol
  • 2016
2 Excerpts

Similar Papers

Loading similar papers…