245 Citations
ST-segment elevation myocardial infarction
- Medicine, BiologyNature Reviews Disease Primers
- 2019
Primary percutaneous coronary intervention (PCI) has become the preferred reperfusion strategy in patients with STEMI; if PCI cannot be performed within 120 minutes of STEMI diagnosis, fibrinolysis therapy should be administered to dissolve the occluding thrombus.
Reperfusion Strategies in Acute Myocardial Infarction: State of the Art
- MedicineInternational Journal of Cardiovascular Sciences
- 2021
A systematic review of different reperfusion strategies for STEMI was conducted, including randomized controlled trials that included major cardiovascular events (MACE), and systematic reviews in the last 5 years through the PRISMA ( Preferred Reporting Items for Systematic Reviews and Meta-Analysis) methodology.
Therapeutic Peptides to Treat Myocardial Ischemia-Reperfusion Injury
- Medicine, BiologyFrontiers in Cardiovascular Medicine
- 2022
Therapeutic peptides will be presented depending on their interacting mechanisms (apoptosis, necroptosis, and inflammation) reported as playing an important role in reperfusion injury following myocardial ischemia, to develop new cardioprotective strategies to decrease morbidity/mortality of CVD.
Diagnosis and Treatment of Acute Coronary Syndromes: A Review.
- MedicineJAMA
- 2022
In high-risk patients with NSTE-ACS and no contraindications, prompt invasive coronary angiography and percutaneous or surgical revascularization within 24 to 48 hours are associated with a reduction in death from 6.5% to 4.9%.
EVs predict the outcomes in patients with acute myocardial infarction.
- Biology, MedicineTissue & cell
- 2022
The impact of optimal medical therapy on patients with recurrent acute myocardial infarction: Subanalysis from the BleeMACS study.
- MedicineInternational journal of cardiology
- 2020
Myocardial perfusion scintigraphy in myocardial infarction — impact of ST-segment elevation and of Diabetes mellitus
- MedicinePorto Biomedical Journal
- 2022
The presence of ST-segment elevation but not the presence of Diabetes mellitus is associated with different patterns of MPS in patients with MI, with significantly larger values both for percentage and absolute areas of perfusion defects both at rest and in a stress situation.
The diagonal branches and outcomes in patients with anterior ST- elevation myocardial infarction
- MedicineBMC Cardiovascular Disorders
- 2020
Landmark analysis indicated that the significant differences in 18-month outcomes between the two groups mainly resulted from the differences during the hospitalization, and multivariate Cox proportional hazards analysis found that D flow loss before primary PCI was independent factor predicting short- and long-term outcomes in patients with anterior STEMI.
Targeting Inflammation After Myocardial Infarction
- Medicine, BiologyCurrent Cardiology Reports
- 2020
In patients with AMI, modulation of residual inflammation via various inflammatory pathways and mediators may hold promise for further reducing MACE.
Culprit vessel-related myocardial mechanics and prognostic implications following acute myocardial infarction
- MedicineClinical Research in Cardiology
- 2019
CMR allows IRA-specific phenotyping and characterisation of morphologic and functional changes that carry infarct-specific prognostic implications, and may represent novel diagnostic and therapeutic targets following AMI.
References
SHOWING 1-10 OF 62 REFERENCES
Randomized trial of preventive angioplasty in myocardial infarction.
- MedicineThe New England journal of medicine
- 2013
In patients with STEMI and multivessel coronary artery disease undergoing infarct-artery PCI, preventive PCI in noninfarct coronary arteries with major stenoses significantly reduced the risk of adverse cardiovascular events, as compared with PCI limited to the infarCT artery.
How can we optimize the processes of care for acute coronary syndromes to improve outcomes?
- MedicineAmerican heart journal
- 2014
Thrombus aspiration during ST-segment elevation myocardial infarction.
- MedicineThe New England journal of medicine
- 2013
Routine thrombus aspiration before PCI as compared with PCI alone did not reduce 30-day mortality among patients with STEMI, and results were consistent across all major prespecified subgroups, including subgroups defined according toThrombus burden and coronary flow before PCI.
Early versus delayed invasive intervention in acute coronary syndromes.
- MedicineThe New England journal of medicine
- 2009
Early intervention did not differ greatly from delayed intervention in preventing the primary outcome, but it did reduce the rate of the composite secondary outcome of death, myocardial infarction, or refractory ischemia and was superior to delayed Intervention in high-risk patients.
Mechanical complications after percutaneous coronary intervention in ST-elevation myocardial infarction (from APEX-AMI).
- MedicineThe American journal of cardiology
- 2010
Bivalirudin during primary PCI in acute myocardial infarction.
- MedicineThe New England journal of medicine
- 2008
In patients with ST-segment elevation myocardial infarction who are undergoing primary PCI, anticoagulation with bivalirudin alone, as compared with heparin plus glycoprotein IIb/IIIa inhibitors, results in significantly reduced 30-day rates of major bleeding and net adverse clinical events.
Current State of Radial Artery Catheterization in ST-Elevation Myocardial Infarction.
- MedicineProgress in cardiovascular diseases
- 2015
Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
- MedicineThe Lancet
- 2015
Culprit vessel versus immediate complete revascularization in patients with ST-segment myocardial infarction-a systematic review.
- MedicineAmerican heart journal
- 2015
Effect of platelet inhibition with cangrelor during PCI on ischemic events.
- MedicineThe New England journal of medicine
- 2013
Cangrelor significantly reduced the rate of ischemic events, including stent thrombosis, during PCI, with no significant increase in severe bleeding.