Acute myeloid leukemia with inv(16)(p13q22): involvement of cervical lymph nodes and tonsils is common and may be a negative prognostic sign.

@article{Billstrm2002AcuteML,
  title={Acute myeloid leukemia with inv(16)(p13q22): involvement of cervical lymph nodes and tonsils is common and may be a negative prognostic sign.},
  author={Rolf Billstr{\"o}m and Tomas Ahlgren and Albert N B{\'e}k{\'a}ssy and Claes Malm and Tor O Olofsson and Martin H{\"o}glund and Felix Mitelman and Bertil Johansson},
  journal={American journal of hematology},
  year={2002},
  volume={71 1},
  pages={
          15-9
        }
}
Acute myeloid leukemia (AML) with inv(16)(p13q22) or the variant t(16;16)(p13;q22), is strongly associated with the FAB subtype M4Eo. A high incidence of CNS involvement was reported in the 1980s, but otherwise little is known about the pattern of extamedullary leukemia (EML) manifestations in this AML type. We have compiled clinical and cytogenetic data on 27 consecutive AML cases with inv(16)/t(16;16) from southern Sweden. In general, these AMLs displayed the clinical features that have… CONTINUE READING
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