Acute liver failure: redefining the syndromes

  title={Acute liver failure: redefining the syndromes},
  author={R. Williams and S. Schalm and J. O'Grady},
  journal={The Lancet},
  • R. Williams, S. Schalm, J. O'Grady
  • Published 1993
  • Medicine
  • The Lancet
  • Existing definitions of clinical syndromes in acute liver failure do not accurately reflect important differences in clinical features and prognosis. Based on a large series of patients with acute liver failure treated at King's College Hospital, London between 1972 and 1985, we propose a new terminology. Hyperacute liver failure is our suggested term for cases in which encephalopathy occurs within 7 days of the onset of jaundice; this group includes the sizeable cohort likely to survive with… CONTINUE READING
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