Acute kidney injury in acute liver failure: a review.

  title={Acute kidney injury in acute liver failure: a review.},
  author={Joanna K. Moore and Eleanor R Love and Darren G N Craig and P C Hayes and Kenneth James Simpson},
  journal={Expert review of gastroenterology & hepatology},
  volume={7 8},
Acute liver failure is a rare and often devastating condition consequent on massive liver cell necrosis that frequently affects young, previously healthy individuals resulting in altered cognitive function, coagulopathy and peripheral vasodilation. These patients frequently develop concurrent acute kidney injury (AKI). This abrupt and sustained decline in renal function, through a number of pathogenic mechanisms such as renal hypoperfusion, direct drug-induced nephrotoxicity or sepsis/systemic… CONTINUE READING