Acute kidney injury

@article{Ronco2019AcuteKI,
  title={Acute kidney injury},
  author={Claudio Ronco and Rinaldo Bellomo and John A. Kellum},
  journal={The Lancet},
  year={2019},
  volume={394},
  pages={1949-1964}
}

Defining Acute Kidney Injury.

Acute kidney injury pathology and pathophysiology: a retrospective review

TLDR
This review aims to show the pathology of AKI, including glomerular and tubular diseases, which can be a guide for treatment and assessment of prognosis.

Emodin-Mediated Treatment of Acute Kidney Injury

TLDR
Clinical evidence has demonstrated that three-month treatment with TCM produced better clinical outcomes in terms of clinical effectiveness rate and improvement in renal function compared with Western medicine.

Preventive strategies for acute kidney injury in cancer patients

TLDR
A multidisciplinary clinical approach that incorporates adequate assessment, use of appropriate preventive measures and early intervention is essential to reduce the incidence of this life-threatening condition in cancer patients.

AACC Guidance Document on Laboratory Investigation of Acute Kidney Injury.

TLDR
This guidance document is intended to inform clinicians and laboratorians on the best practices for the laboratory investigation of AKI, based on expert recommendations where the preponderance of evidence is available.
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References

SHOWING 1-10 OF 181 REFERENCES

Acute kidney injury

Global epidemiology and outcomes of acute kidney injury

TLDR
The global epidemiology of acute kidney injury is described and the influence of modifiable and non-modifiable AKI risk factors, delayed diagnosis, variation in diagnostic criteria and disparities in access to health care are also discussed.

Acute kidney injury in sepsis

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU and accounts for

CRRT for sepsis-induced acute kidney injury

TLDR
The present review summarizes the recent insights and results from large randomized and nonrandomized trials in the area of RRT applied both as supportive measures for kidney failure and blood purification techniques for sepsis syndrome.

Acute Kidney Injury: Definition, Pathophysiology and Clinical Phenotypes.

TLDR
The view for AKI is beginning to change from a single organ failure syndrome to a syndrome where the kidney plays an active role in the progress of multi-organ dysfunction.

The distant organ effects of acute kidney injury.

TLDR
Clinical and preclinical studies of AKI are summarized to summarized and growing evidence implicates renal injury as an instigator and multiplier of pulmonary, cardiac, hepatic, and neurologic dysfunction and its role in distant organ injury.

Sepsis-induced acute kidney injury

TLDR
The recognition that other mechanisms are at play opens the possibility to better understand the processes of injury and repair, and provides an invaluable opportunity to design mechanism-targeted therapeutic interventions.

Acute kidney injury and chronic kidney disease as interconnected syndromes.

TLDR
Recent epidemiologic and mechanistic studies suggest that the two syndromes of diminished kidney function are not distinct entities but rather are closely interconnected — chronic kidney disease is a risk factor for acute kidney injury, acute kidneys injury is arisk factor for the development of chronic kidney Disease, and both acute kidney disease and chronic kidney health are risk factors for cardiovascular disease.

Septic Acute Kidney Injury: New Concepts

TLDR
Experimental observations provide proof of concept that septic AKI can occur in the setting of renal hyperemia and that ischemia is not necessary for loss of glomerular filtration rate (GFR) to occur, and suggest that similar hemodynamic event may occur in man.

Current state of the art for renal replacement therapy in critically ill patients with acute kidney injury

TLDR
New knowledge and recent advances for the provision of RRT for critically ill patients with AKI are summarized in this concise review.
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