Acute ischemic stroke lesion measurement on diffusion-weighted imaging--important considerations in designing acute stroke trials with magnetic resonance imaging.

@article{Rivers2007AcuteIS,
  title={Acute ischemic stroke lesion measurement on diffusion-weighted imaging--important considerations in designing acute stroke trials with magnetic resonance imaging.},
  author={Carly S. Rivers and Joanna M. Wardlaw and Paul A. Armitage and Mark E. Bastin and Peter J. Hand and Martin Dennis},
  journal={Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association},
  year={2007},
  volume={16 2},
  pages={64-70}
}
BACKGROUND In acute ischemic stroke, magnetic resonance diffusion-weighted imaging (DWI) is increasingly used to select patients for inclusion or as a surrogate outcome marker in clinical trials, or in routine practice. Little is known of what factors might affect DWI lesion size measurement. We examined morphologic factors that might affect DWI lesion measurement. METHODS On DWI obtained less than 24 hours after stroke, we categorized lesions according to DWI appearance (solitary or… CONTINUE READING
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