Acute interstitial nephritis.

@article{Praga2010AcuteIN,
  title={Acute interstitial nephritis.},
  author={Manuel Praga and Ester Gonzalez},
  journal={Kidney international},
  year={2010},
  volume={77 11},
  pages={956-61}
}
Acute interstitial nephritis (AIN) represents a frequent cause of acute kidney injury, accounting for 15-27% of renal biopsies performed because of this condition. By and large, drug-induced AIN is currently the commonest etiology of AIN, with antimicrobials and nonsteroidal anti-inflammatory drugs being the most frequent offending agents. Pathogenesis is based on an immunologic reaction against endogenous nephritogenic antigens or exogenous antigens processed by tubular cells, with cell… CONTINUE READING
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