Acute intermittent porphyria presenting as acute pancreatitis and posterior reversible encephalopathy syndrome.

@article{Shen2008AcuteIP,
  title={Acute intermittent porphyria presenting as acute pancreatitis and posterior reversible encephalopathy syndrome.},
  author={Feng-Chih Shen and Ching-Hua Hsieh and Chi-Ren Huang and Chun-Chung Lui and Wei-Chen Tai and Yao-Chung Chuang},
  journal={Acta neurologica Taiwanica},
  year={2008},
  volume={17 3},
  pages={
          177-83
        },
  url={https://api.semanticscholar.org/CorpusID:43234107}
}
A 60-year-old non-alcoholic male who had typical manifestations of AIP, including abdominal pain, constipation, tachycardia, hypertension, mental disturbances, psychiatric manifestations, seizures, peripheral neuropathy, and excessive excretion of porphyrin precursors in urine is reported.
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Acute Intermittent Porphyria Presenting with Posterior Reversible Encephalopathy Syndrome: A Rare Cause of Abdominal Pain and Seizures

A young woman who presented with AIP and PRES with seizures is described, which is a rare cause of Abdominal Pain and Seizures and should be considered when a patient presents with unexplained abdominal pain and seizures.

Acute intermittent porphyria leading to posterior reversible encephalopathy syndrome (PRES): a rare cause of abdominal pain and seizures

A case of AIP and PRES in a young woman is described and drugs used in the management of seizures may worsen an attack of Aip.

Management of acute intermittent porphyria

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[Posterior reversible encephalopathy syndrome as a presentation of acute intermittent porphyria].

The authors describe a clinical case of posterior reversible encephalopathy syndrome (PRES) in a 36-year-old female patient due to the first onset of not previously diagnosed acute intermittent porphyria, the first report of a similar association confirmed by magnetic resonance imaging (MRI) in the Russian literature.

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It is suggested to consider posterior reversible encephalopathy syndrome in the differential diagnosis of a neurological deterioration preceded by hypertension and/or septic state, even without other “typical” clinical features.

26 References

A case of acute intermittent porphyria with acute pancreatitis

A case of acute pancreatitis in a 29-year-old female associated with an attack of acute intermittent porphyria (AIP) is reported and it is possible that these findings are etiologically connected in this patient.

Acute Porphyrias: Pathogenesis of Neurological Manifestations

The present evidence suggests that multiple mechanisms interact in causing the varied symptoms, including ALA interaction with GABA receptors, altered tryptophan metabolism, and possibly heme depletion in nerve cells.

Acute intermittent porphyria with relapsing acute pancreatitis and unconjugated hyperbilirubinemia without overt hemolysis.

Acute intermittent porphyria presenting as a diffuse encephalopathy

Because diffusion‐weighted MR imaging and spectroscopy were normal, the lesions are likely caused by reversible vasogenic edema and transient breakdown of the blood–brain barrier.

MR imaging of acute intermittent porphyria mimicking reversible posterior leukoencephalopathy syndrome

The case of a 30-year-old woman who had suffered her first attack of acute intermittent porphyria and developed several generalized seizures, and hallucinations, and exhibited a progressive deterioration of the consciousness is presented, the first report concerning a completely reversible PLS in AIP.

[Acute pancreatitis associated with acute intermittent porphyria].

It seems to be necessary to pay attention to the combination of these diseases, since this patient developed acute pancreatitis following the attack of AIP, and it is possible that AIP might have caused the acute pancreatritis.

Diffusion-Weighted Magnetic Resonance Imaging of Porphyric Encephalopathy: A Case Report

A patient with acute intermittent porphyria (AIP) with the clinical presentation as cortical blindness is described, which suggests vasogenic edema may be the basis for the pathophysiology of porphyric encephalopathy.

Acute intermittent porphyria with peripheral neuropathy: A follow-up study after hematin treatment

Acute porphyria presenting with hyperamylasemia

An association between elevation of the serum amylase and lipase with acute porphyria is suggested, which can lead to delay in establishing the diagnosis of acute Porphyria.

Acute intermittent porphyria

A patient with AIP followed for 31 years with multiple episodes of hyponatremia during AIP exacerbations is presented and the clinicopathologic correlation and possible explanations for the morphologic findings are discussed, including discrete hypothalamic changes.