Acute injury to superficial cortex leads to a decrease in synaptic inhibition and increase in excitation in neocortical layer V pyramidal cells.

@article{Yang2007AcuteIT,
  title={Acute injury to superficial cortex leads to a decrease in synaptic inhibition and increase in excitation in neocortical layer V pyramidal cells.},
  author={Lie Yang and L. Benardo and H. Valsamis and D. S. Ling},
  journal={Journal of neurophysiology},
  year={2007},
  volume={97 1},
  pages={
          178-87
        }
}
Injury to the superficial layers of cerebral cortex produces alterations in the synaptic responses of local circuits that promote the development of seizures. To further delineate the specific changes in synaptic strength that are induced by this type of cortical injury, whole cell voltage-clamp recordings were used to examine evoked and spontaneous synaptic events from layer V pyramidal cells in coronal slices prepared from surgically traumatized rat neocortices in which the superficial third… Expand
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