Acute hydrocortisone myopathy in acute severe asthma.

@article{Knox1986AcuteHM,
  title={Acute hydrocortisone myopathy in acute severe asthma.},
  author={Alan J. Knox and B. H. Mascie-Taylor and Martin F. Muers},
  journal={Thorax},
  year={1986},
  volume={41 5},
  pages={
          411-2
        }
}
Myopathy of insidious onset produced by corticosteroids is well recognised. In recent years acute myopathy has been reported in patients with acute severe asthma treated with 3-4 g of intravenous hydrocortisone a day.1 2 It has been argued that to minimise the risks of this the dose should be no more than 1 g of hydrocortisone a day.2 There is evidence that 1 g/day is an effective regimen.3 We report a further case of acute myopathy occurring in a patient who never received more than 1 g/day of… CONTINUE READING

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Pp 146; free of charge

  • 1983. Ed FE Hargreave, AJ Woolcock
  • Astra Pharmaceuticals Canada Ltd
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