Acute genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity.

@article{Akimoto2005AcuteGT,
  title={Acute genitourinary toxicity after high-dose-rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity.},
  author={Tetsuo Akimoto and Kazuto Ito and Jun-Ichi Saitoh and Shin-ei Noda and Koichi Harashima and Hideyuki Sakurai and Yuko Nakayama and Takumi Yamamoto and Kazuhiro Suzuki and Takashi Nakano and Hideo Niibe},
  journal={International journal of radiation oncology, biology, physics},
  year={2005},
  volume={63 2},
  pages={463-71}
}
PURPOSE Several investigations have revealed that the alpha/beta ratio for prostate cancer is atypically low, and that hypofractionation or high-dose-rate (HDR) brachytherapy regimens using appropriate radiation doses may be expected to yield tumor control and late sequelae rates that are better or at least as favorable as those achieved with conventional radiation therapy. In this setting, we attempted treating localized prostate cancer patients with HDR brachytherapy combined with… CONTINUE READING

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